A lot has been said over the last few months about the possibility of Nintendo using cartridges for the NX– in fact, this is something that seems to be backed up by substantial evidence. It would make sense for Nintendo, too, especially since flash memory is now cheap and commoditized- meaning that all the disadvantages of cartridges no longer hold, but the advantages all do.
It is also possible that the ‘cartridge’ portion of the listing refers to the long speculated upon portable version of the NX. The NX is speculated to have a handheld component and a console component, both sharing the same games and software– so it is possible that it will be the handheld version of the NX, which will be running Zelda from a cart, while the console version still uses discs.
It’s hard to know, for now. Until the NX is revealed, and we know what it is, all we can do, really, is speculate.
Source: Rheena.com